Chemical Composition and Anticandidal Activity of Essential Oils Obtained from Different Parts of Prangos heyniae H. Duman & M. F. Watson

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Karahisar E., KÖSE Y. B., İŞCAN G., KÜRKÇÜOĞLU M., TUGAY O.

RECORDS OF NATURAL PRODUCTS, vol.16, no.1, pp.74-83, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.25135/rnp.246.21.02.1971
  • Journal Name: RECORDS OF NATURAL PRODUCTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, ABI/INFORM, CAB Abstracts, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.74-83
  • Keywords: Apiaceae, essential oil, GC/MS, Prangos heyniae, anticandidal activity, FERULACEA L. LINDL., ANTIBACTERIAL ACTIVITY, ANTIMICROBIAL ACTIVITY, PABULARIA LINDL., VOLATILE OILS, AERIAL PARTS, CONSTITUENTS, FRUITS, LEAVES, HYDRODISTILLATION
  • Anadolu University Affiliated: Yes

Abstract

The chemical compositions and anticandidal activities of the essential oils from the aerial parts, inflorescence, and roots of the endemic P. heyniae H. Duman & M. F.Watson were evaluated. Hydrodistillation was used to isolate the essential oils and the chemical analyses were performed both by GC-FID and GC/MS, respectively. Forty-four compounds constituting 94.4% of aerial parts, thirty-nine compounds constituting 99.5% of inflorescence, and twenty-five compounds representing 100.0% of root essential oil were characterized. The main compounds of the aerial parts oil were elemol (36.2%), beta-bisabolenal (14.1%), and germacrene D (12.7%). Main compounds of inflorescence oil were alpha-bisabolenal (21.6%) germacrene D (15.6%), and germacrene B (12.4%) while the roots oil were alpha-pinene (44.8%), limonene (15.3%), beta-pinene (12.5%), and delta-3-carene (10.2%), respectively. The in vitro anticandidal activity of the essential oils were evaluated against several Candida strains by using partly modified CLSI broth microdilution method M27-A2. The tested essential oil showed relatively weak effects against pathogenic Candida strains compared to standard antifungal agents.