The interactions of cephalosporins on polyol pathway enzymes from sheep kidney
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, vol.124, no.1, pp.35-44, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 124 Issue: 1
- Publication Date: 2018
- Doi Number: 10.1080/13813455.2017.1358749
- Journal Name: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.35-44
- Keywords: Aldose reductase, sorbitol dehydrogenase, cephalosporins, inhibition, diabetes, REDUCTASE INHIBITORY-ACTIVITY, ALDOSE REDUCTASE, CARBONIC-ANHYDRASE, IN-VITRO, KINETIC-PROPERTIES, ANTIBIOTIC DRUG, SORBITOL, GLUCOSE-6-PHOSPHATE-DEHYDROGENASE, ERYTHROCYTES, PURIFICATION
- Anadolu University Affiliated: Yes
Abstract
Context: Cephalosporins are derived from the fungus Acremonium. Due to their strong bactericidal ability, these drugs have to a wide usage in medicine.Objective: An investigation of the effects on sheep renal aldose reductase (AR) and sorbitol dehydrogenase (SDH) of cefoperazone, cefazolin, cefuroxime, ceftazidime and ceftriaxone as cephalosporin drugs was carried out in the present study.