The interactions of cephalosporins on polyol pathway enzymes from sheep kidney

ŞENGÜL B., BEYDEMİR Ş.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, cilt.124, sa.1, ss.35-44, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 124 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1080/13813455.2017.1358749
  • Dergi Adı: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.35-44
  • Anahtar Kelimeler: Aldose reductase, sorbitol dehydrogenase, cephalosporins, inhibition, diabetes, REDUCTASE INHIBITORY-ACTIVITY, ALDOSE REDUCTASE, CARBONIC-ANHYDRASE, IN-VITRO, KINETIC-PROPERTIES, ANTIBIOTIC DRUG, SORBITOL, GLUCOSE-6-PHOSPHATE-DEHYDROGENASE, ERYTHROCYTES, PURIFICATION
  • Anadolu Üniversitesi Adresli: Evet

Özet

Context: Cephalosporins are derived from the fungus Acremonium. Due to their strong bactericidal ability, these drugs have to a wide usage in medicine.Objective: An investigation of the effects on sheep renal aldose reductase (AR) and sorbitol dehydrogenase (SDH) of cefoperazone, cefazolin, cefuroxime, ceftazidime and ceftriaxone as cephalosporin drugs was carried out in the present study.