Composition, enantiomeric distribution, and antimicrobial activity of Tanacetum argenteum subsp flabellifolium essential oil
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol.45, no.5, pp.714-719, 2007 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 45 Issue: 5
- Publication Date: 2007
- Doi Number: 10.1016/j.jpba.2007.08.006
- Journal Name: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.714-719
- Keywords: Tanacetum argenteum subsp.flabellifolium, Asteraceae, enantiomeric distribution, GC-MS, MDGC-MS, antimicrobial activity, SOLID-PHASE MICROEXTRACTION, SESQUITERPENE LACTONES, CHEMICAL-COMPOSITION, VULGARE L., EXTRACTION, PARTHENIUM, CANUM
- Anadolu University Affiliated: Yes
Abstract
Tanacetum argenteum (Lam.) Willd. subsp.flabellifolium, (Boiss. & Heldr.) Grierson of Asteraceae is an endemic species in Turkey. Hydrodistillation of aerial parts using a Clevenger apparatus yielded an essential oil, which was subsequently analyzed by gas chromatography-mass spectroscopy (GC-MS). alpha-Pinene (29%), (E)-sesquilavandulol (16%), and camphor (14%) were found as main constituents. Enantiomeric distribution of the monoterpenes a-pinene and camphor was determined on a fused silica Lipodex E capillary column using a multidimensional gas chromatography-mass spectroscopy (MDGC-MS) system, (-)-alpha-pinene (86%), (+)-a-pinene (14%), and (-)-camphor (100%) enantiomeric distributions were found in the oil. Furthermore, antimicrobial activity of the oil was carried out using a micro-dilution assay against human pathogenic bacteria and the yeast Candida albicans resulting in moderate inhibitory concentrations (MIC = 125 mu g/mL). (c) 2007 Elsevier B.V. All rights reserved.