Mirtazapine suppresses sterile inflammation through NLRP3-inflammasome in diabetic rat kidney

ŞAHİN E., Bektur E., BURUKOĞLU DÖNMEZ D., Baycu C., CAN Ö. D., ŞAHİNTÜRK V.

ACTA HISTOCHEMICA, vol.121, no.3, pp.289-296, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 121 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.1016/j.acthis.2019.01.007
  • Journal Name: ACTA HISTOCHEMICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.289-296
  • Keywords: Diabetes mellitus, Kidney, Mirtazapine, NLRP3, Caspase-1, NLRP3 INFLAMMASOME, SIGNALING PATHWAYS, ACTIVATION, NEPHROPATHY, INTERLEUKIN-1-BETA, HIPPOCAMPUS, PROTEIN, CORTEX, DAMAGE, CELLS
  • Anadolu University Affiliated: Yes

Abstract

Aim The aim of this study was to investigate the effects of mirtazapine, which is anti-oxidative and antidepressant agent, on the kidney damage caused by diabetes mellitus.