Akademik Veri Yönetim Sistemi
INDIAN JOURNAL OF ANIMAL RESEARCH, cilt.57, sa.9, ss.1240-1243, 2023 (SCI-Expanded)
Background: This study aimed to evaluate the
therapeutic efficacy of paromomycin sulphate on serum amyloid A (SAA)
and haptoglobin (Hp) in Cryptosporidiosis in goat kids.
Methods:
In the study, stool samples were taken from the kids and
Cryptosporidium was detected via the rapid test kit. Then, by examining
the same stool samples microscopically, we included 9 kids in the study
and 50 mg/kg of paromomycin sulphate was administered to the kids in
which Cryptosporidium spp. was detected for five days as a treatment.
For the SAA and Hp estimation, blood samples were drawn from the kids in
the pre and post treatment stages.
Result: In
the kids with Cryptosporidium, the concentrations of SAA and Hp were
measured as (SAA; 17.10±4.18 ng/mL Hp; 2.68±1.08 µg/mL) in pre-treatment
and as (SAA; 9,71±4,13 ng/mL, Hp; 1,23±0,64 µg/mL) in the
post-treatment stage (p<0,05). In accordance with these findings, we
suggest that routine measurements of SAA and Hp concentrations of the
goat kids with diarrhea due to cryptosporidiosis could be of value in
follow up of treatment, determining the severity of the infection,
selection of therapy and monitoring the efficacy of the preferred
treatment protocol and in detection of subclinical infections.