Bacterial Biotransformation and Anticancer Activities of Betulin against A549, HepG2 and 5RP7 Cancer Cell Lines
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.21, no.12, pp.1581-1593, 2021 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 21 Issue: 12
- Publication Date: 2021
- Doi Number: 10.2174/1871520620666201029102400
- Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
- Page Numbers: pp.1581-1593
- Keywords: Anticancer, apoptosis, betulin, biotransformation, bacteria, cancer cell lines, ACID INDUCES APOPTOSIS, IN-VITRO, DERIVATIVES, PROLIFERATION, INHIBITION, EXTRACT, GROWTH
- Anadolu University Affiliated: Yes
Abstract
Background: A pentacyclic lupenane-type natural triterpenoid, betulin, has attracted attention in the field of medicinal chemistry since it exhibited a variety of biological activities, including anticancer activity.