Bacterial Biotransformation and Anticancer Activities of Betulin against A549, HepG2 and 5RP7 Cancer Cell Lines

KIRAN İ., AKALIN ÇİFTÇİ G., ATLI EKLİOĞLU Ö., Akkaya S. G. K.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.21, no.12, pp.1581-1593, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 12
  • Publication Date: 2021
  • Doi Number: 10.2174/1871520620666201029102400
  • Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.1581-1593
  • Keywords: Anticancer, apoptosis, betulin, biotransformation, bacteria, cancer cell lines, ACID INDUCES APOPTOSIS, IN-VITRO, DERIVATIVES, PROLIFERATION, INHIBITION, EXTRACT, GROWTH
  • Anadolu University Affiliated: Yes

Abstract

Background: A pentacyclic lupenane-type natural triterpenoid, betulin, has attracted attention in the field of medicinal chemistry since it exhibited a variety of biological activities, including anticancer activity.