BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol.23, no.24, pp.6764-6768, 2013 (SCI-Expanded)
Article / Article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
Imidazole, Antimicrobial, Brine-Shrimp test, Anticancer, ANTIBACTERIAL, ANTITUMOR, RESISTANT
Anadolu University Affiliated:
In this work, some new 2-[(4,5-dimethyl-1-(arylamino)-1H-imidazol-2-yl)thio]-1-(aryl) ethanone derivatives were synthesized and investigated for their antibacterial, antifungal and anticancer activities. Toxicity of the most effective compounds was established by performing Brine-Shrimp lethality assay. Antifungal activity of the compounds was found to be higher than antibacterial and anticancer activities of the compounds. (C) 2013 Elsevier Ltd. All rights reserved.