Interaction of cancer cells with magnetic nanoparticles modified by methacrylamido-folic acid

Creative Commons License

SALTAN N., KUTLU H. M., HÜR D., Iscan A., Say R.

INTERNATIONAL JOURNAL OF NANOMEDICINE, cilt.6, ss.477-484, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6
  • Basım Tarihi: 2011
  • Doi Numarası: 10.2147/ijn.s16803
  • Dergi Adı: INTERNATIONAL JOURNAL OF NANOMEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.477-484
  • Anahtar Kelimeler: folic acid, apoptosis, nanoparticles, transmission electron microscopy, ANNEXIN-V, FE3O4 NANOPARTICLES, APOPTOTIC CELLS, FOLATE BINDING, IN-VITRO, PHOSPHATIDYLSERINE, EXPRESSION, INHIBITION, DESIGN
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: Magnetic nanoparticles show great promise for use as tools in a wide variety of biomedical applications. The purpose of this study was to investigate the potential effects of methacrylamido-folic acid (Ma-Fol)-modified magnetic nanoparticles on 5RP7 (H-ras-transformed rat embryonic fibroblasts) and NIH/3T3 (normal mouse embryonic fibroblasts).