Interaction of cancer cells with magnetic nanoparticles modified by methacrylamido-folic acid

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SALTAN N., KUTLU H. M., HÜR D., Iscan A., Say R.

INTERNATIONAL JOURNAL OF NANOMEDICINE, vol.6, pp.477-484, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6
  • Publication Date: 2011
  • Doi Number: 10.2147/ijn.s16803
  • Journal Name: INTERNATIONAL JOURNAL OF NANOMEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.477-484
  • Keywords: folic acid, apoptosis, nanoparticles, transmission electron microscopy, ANNEXIN-V, FE3O4 NANOPARTICLES, APOPTOTIC CELLS, FOLATE BINDING, IN-VITRO, PHOSPHATIDYLSERINE, EXPRESSION, INHIBITION, DESIGN
  • Anadolu University Affiliated: Yes

Abstract

Background: Magnetic nanoparticles show great promise for use as tools in a wide variety of biomedical applications. The purpose of this study was to investigate the potential effects of methacrylamido-folic acid (Ma-Fol)-modified magnetic nanoparticles on 5RP7 (H-ras-transformed rat embryonic fibroblasts) and NIH/3T3 (normal mouse embryonic fibroblasts).