Synthesis of some 3-arylamino-5-aryloxymethyl[1,2,4]triazole derivatives and their antimicrobial activity
Pharmaceutica Acta Helvetiae, vol.72, no.5, pp.285-290, 1998 (Scopus)
- Publication Type: Article / Article
- Volume: 72 Issue: 5
- Publication Date: 1998
- Doi Number: 10.1016/s0031-6865(97)00035-6
- Journal Name: Pharmaceutica Acta Helvetiae
- Journal Indexes: Scopus
- Page Numbers: pp.285-290
- Keywords: 3-Amino[1,2,4]triazole, Antimicrobial activity, Hydrazide, Thiourea
- Anadolu University Affiliated: Yes
Abstract
In this study, some 3-arylamino-5-aryloxymethyl[1,2,4]triazole derivatives were synthesized by reacting S-methyl-N'-arylisothiouronium iodide and 2- (aryloxy)alkanoic acid hydrazide. The structural elucidation of the compounds was performed by IR, 1H-NMR and MS spectroscopic data and elemental analyses results. Antibacterial and antifungal activities of the compounds were examined.