LETTERS IN DRUG DESIGN & DISCOVERY, vol.14, no.8, pp.910-917, 2017 (SCI-Expanded)
Article / Article
LETTERS IN DRUG DESIGN & DISCOVERY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Antiproliferative, apoptosis, cytotoxicity, hydrazone, piperazine, biological activities, PROCASPASE-ACTIVATING COMPOUND, ANNEXIN-V, BENZIMIDAZOLE DERIVATIVES, BIOLOGICAL EVALUATION, AGENTS
Anadolu University Affiliated:
Background: Compounds bearing ortho-hydroxy N-acyl hydrazone moiety have been reported with high anticancer activity acting by increasing the enzymatic activity of procaspase-3 in cancer cells and therefore inducing apoptosis in some tumour models.