Synthesis of some 6,8-diarylimidazo[1,2-a]pyrazine derivatives by using either reflux or microwave irradiation method and investigation of their anticancer activities

Demirayak S., Kayagil I.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.42, no.2, pp.319-325, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 2
  • Publication Date: 2005
  • Doi Number: 10.1002/jhet.5570420224
  • Journal Name: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC), Current Chemical Reactions (CCR)
  • Page Numbers: pp.319-325
  • Anadolu University Affiliated: No

Abstract

In order to obtain some 6,8-diarylimidazo[1,2-a]pyrazines, 1-(2-aryl-2-oxoethyl)-2-aryloylimidazole derivatives were reacted with ammonium acetate in acetic acid by using a new method different from that found in the literature. Anticancer activities of the compounds obtained were evaluated and the noticeable activity values were reported.