Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I

Demir Y., TÜRKEŞ C., BEYDEMİR Ş.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.20, sa.7, ss.887-896, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 7
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1871520620666200218110645
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.887-896
  • Anahtar Kelimeler: Paraoxonase, chromatography, inhibition, antineoplastic agent, molecular docking, enzyme-drug interactions, HUMAN SERUM PARAOXONASE-1, IRINOTECAN HYDROCHLORIDE, PURIFICATION, VITRO, PON1, CYCLOPHOSPHAMIDE, AZACITIDINE, THYMIDINE, PROTEINS, CANCER
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: Currently, most of the drugs used in clinical applications show their pharmacological influences by inhibiting or activating enzymes. Therefore, enzyme inhibitors have an essential place in the drug design for many diseases.