Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I

Demir Y., TÜRKEŞ C., BEYDEMİR Ş.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.20, no.7, pp.887-896, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 7
  • Publication Date: 2020
  • Doi Number: 10.2174/1871520620666200218110645
  • Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.887-896
  • Keywords: Paraoxonase, chromatography, inhibition, antineoplastic agent, molecular docking, enzyme-drug interactions, HUMAN SERUM PARAOXONASE-1, IRINOTECAN HYDROCHLORIDE, PURIFICATION, VITRO, PON1, CYCLOPHOSPHAMIDE, AZACITIDINE, THYMIDINE, PROTEINS, CANCER
  • Anadolu University Affiliated: Yes

Abstract

Background: Currently, most of the drugs used in clinical applications show their pharmacological influences by inhibiting or activating enzymes. Therefore, enzyme inhibitors have an essential place in the drug design for many diseases.