Some Thiazole Derivatives Combined with Different Heterocycles: Cytotoxicity Evaluation and Apoptosis Inducing Studies

YURTTAŞ L., Demir B., AKALIN ÇİFTÇİ G.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.18, no.8, pp.1115-1121, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 8
  • Publication Date: 2018
  • Doi Number: 10.2174/1871520618666180328115314
  • Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1115-1121
  • Keywords: Thiazole, thiazolidinone, lung cancer, glioma, cytotoxicity, apoptosis, hantzsch thiazole, ANTICANCER ACTIVITY EVALUATION, BIOLOGICAL EVALUATION, ANTIPROLIFERATIVE ACTIVITY, BEARING, AGENTS, MOIETY
  • Anadolu University Affiliated: Yes

Abstract

Background: Thiazole ring is an outstanding structure found in many biologically active compounds and clinically available drugs. Because of synthesis simplicity of its derivatives and having a wide range of biological aspects along with high effectiveness, new thiazole derivatives have been studied by medicinal chemists since many years.