MOLECULES, vol.9, no.11, pp.922-938, 2004 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
alkylation of beta-dicarbonyl compounds, spiro derivatives of barbituric acid, 2-chloro-1-(2-chloroethoxy)ethane, theoretical studies
Anadolu University Affiliated:
The alkylation of beta-dicarbonyl compounds in a K2CO3/DMSO system was found to afford O- and C-alkylated derivatives, depending on the type of the P-dicarbonyl compound involved. The alkyl derivatives obtained were used in the synthesis of some new spiro barbituric acid derivatives. Quantum chemical calculations were carried out to elucidate the reaction mechanisms for some typical synthesis.