Synthesis and Anticandidal Activities of Some Aryl (5-Chloro-Benzofuran-2-yl) Ketoximes

KARABURUN A. Ç.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.16, no.4, pp.427-436, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.2174/1570180816666181207155701
  • Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.427-436
  • Keywords: Aryl (5-chloro-benzofuran-2-yl) ketoximes, Anticandidal activity, Ergosterol inhibition, 14-alpha demethylase, docking study, antifungal activity, INVASIVE FUNGAL-INFECTIONS, MOLECULAR-BASIS, BENZOFURAN, ANTIFUNGAL, DISCOVERY, DESIGN, DERIVATIVES, RESISTANCE, EPIDEMIOLOGY, OPTIMIZATION
  • Anadolu University Affiliated: Yes

Abstract

Background: In this study, some aryl (5-chloro-benzofuran-2-yl) ketoximes and their ethers were synthesised to evaluate their antifungal activity against C. albicans, C. glabrata, C. krusei, and C. parapsilosis.