Synthesis and Anticandidal Activities of Some Aryl (5-Chloro-Benzofuran-2-yl) Ketoximes
LETTERS IN DRUG DESIGN & DISCOVERY, vol.16, no.4, pp.427-436, 2019 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 16 Issue: 4
- Publication Date: 2019
- Doi Number: 10.2174/1570180816666181207155701
- Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.427-436
- Keywords: Aryl (5-chloro-benzofuran-2-yl) ketoximes, Anticandidal activity, Ergosterol inhibition, 14-alpha demethylase, docking study, antifungal activity, INVASIVE FUNGAL-INFECTIONS, MOLECULAR-BASIS, BENZOFURAN, ANTIFUNGAL, DISCOVERY, DESIGN, DERIVATIVES, RESISTANCE, EPIDEMIOLOGY, OPTIMIZATION
- Anadolu University Affiliated: Yes
Abstract
Background: In this study, some aryl (5-chloro-benzofuran-2-yl) ketoximes and their ethers were synthesised to evaluate their antifungal activity against C. albicans, C. glabrata, C. krusei, and C. parapsilosis.