Microbial transformation of (-)-carvone
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES, vol.59, no.5-6, pp.389-392, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 59 Issue: 5-6
- Publication Date: 2004
- Doi Number: 10.1515/znc-2004-5-618
- Journal Name: ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.389-392
- Keywords: (-)-carvone, microbial transformation, antimicrobial activity, ESSENTIAL OILS, BIOTRANSFORMATION, CONSTITUENTS, MONOTERPENES, PRODUCTS
- Anadolu University Affiliated: Yes
Abstract
The cyclic monoterpene ketone (-)-carvone was metabolized by the plant pathogenic fungus Absidia glauca. After 4 days of incubation, the diol 10-hydroxy-(+)-neodihydrocarveol was formed. The absolute configuration and structure of the crystalline substance was identified by means of X-ray diffraction and by spectroscopic techniques (MS, IR and NMR). The antimicrobial activity of the substrate and metabolite was assayed with human pathogenic microorganisms.