Evaluation of in vitro anti-cancer effects of Styphnolobium japonicum root extract in human colon (HT-9), brain (U-87), and prostate (PC-3) cancer cell lines

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Okur M. E., KARAKAŞ N., Karadag A. E., Oztunc N., Tosyali I. S., DEMİRCİ F.

ISTANBUL JOURNAL OF PHARMACY, cilt.50, sa.2, ss.103-110, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.26650/istanbuljpharm.2020.0016
  • Dergi Adı: ISTANBUL JOURNAL OF PHARMACY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.103-110
  • Anahtar Kelimeler: Cytotoxicity, Styphnolobium japonicum (Sophora japonica), antioxidant, cancer cell lines, western blotting, flow cytometry analysis, POLY(ADP-RIBOSE) POLYMERASE, MATRINE, ANTIOXIDANT, CLEAVAGE
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background and Aims: Styphnolobium japonicum (L.) Schott. (Sophora japonica) is a medicinal plant applied for various diseases, in the traditional medicine field. The evaluation of methanol extract of S. japonicum root derived from the Pharma Grade plant drug, was performed in terms of various in vitro biological activities.