Evaluation of in vitro anti-cancer effects of Styphnolobium japonicum root extract in human colon (HT-9), brain (U-87), and prostate (PC-3) cancer cell lines

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Okur M. E., KARAKAŞ N., Karadag A. E., Oztunc N., Tosyali I. S., DEMİRCİ F.

ISTANBUL JOURNAL OF PHARMACY, vol.50, no.2, pp.103-110, 2020 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.26650/istanbuljpharm.2020.0016
  • Journal Name: ISTANBUL JOURNAL OF PHARMACY
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.103-110
  • Keywords: Cytotoxicity, Styphnolobium japonicum (Sophora japonica), antioxidant, cancer cell lines, western blotting, flow cytometry analysis, POLY(ADP-RIBOSE) POLYMERASE, MATRINE, ANTIOXIDANT, CLEAVAGE
  • Anadolu University Affiliated: Yes

Abstract

Background and Aims: Styphnolobium japonicum (L.) Schott. (Sophora japonica) is a medicinal plant applied for various diseases, in the traditional medicine field. The evaluation of methanol extract of S. japonicum root derived from the Pharma Grade plant drug, was performed in terms of various in vitro biological activities.