Biological activity and chemical composition of the essential oil from the fruits of Ferula halophila Peşmen
Acta Pharmaceutica Sciencia, vol.61, no.1, pp.81-90, 2023 (Scopus)
- Publication Type: Article / Article
- Volume: 61 Issue: 1
- Publication Date: 2023
- Doi Number: 10.23893/1307-2080.aps6106
- Journal Name: Acta Pharmaceutica Sciencia
- Journal Indexes: Scopus, EMBASE
- Page Numbers: pp.81-90
- Keywords: Antibacterial, anticandidal, essential oil, Ferula halophila
- Anadolu University Affiliated: Yes
Abstract
The hydrodistilled essential oils of the dried fruits of F. halophila Peşmen, an endemic species growing near Salt Lake in Central Anatolia, were analyzed by GC and GC-MS systems; 27 and 24 compounds representing 92.1% and 79.8% of the essential oils were characterized, respectively. The main component of the essential oils was identified as β-phellandrene. The antibacterial and anticandidal effects of the essential oils were determined by using partly modified CLSI methods M7-A7 and M27-A2, respectively. The essential oils from two specimens showed weak to moderate inhibitory effects on the tested pathogenic bacteria (MIC, 125-2000 µg/ mL) and Candida panels (MIC, 156-1250 µg/mL).