Copy For Citation
TEMEL H. E., ALTINTOP M. D., ÖZDEMİR A.
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.15, no.3, pp.333-338, 2018 (ESCI)
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Publication Type:
Article / Article
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Volume:
15
Issue:
3
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Publication Date:
2018
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Doi Number:
10.4274/tjps.20982
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Journal Name:
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
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Journal Indexes:
Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.333-338
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Keywords:
Benzodioxole, cholinesterases, Lipinski's rule of five, pyrazoline, thiazole, ALZHEIMERS-DISEASE, BIOLOGICAL EVALUATION, DRUG DISCOVERY, DUAL INHIBITORS, IDENTIFICATION, MANAGEMENT, TARGETS, BEARING
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Anadolu University Affiliated:
Yes
Abstract
Objectives: In recent years, the design of anticholinesterase agents based on molecular hybridization of pharmacologically active scaffolds has attracted a great deal of interest in medicinal chemistry. For this purpose, we aimed to design and synthesize anticholinesterase agents based on the molecular hybridization of thiazole and pyrazoline scaffolds.