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KAYA ÇAVUŞOĞLU B., KAPLANCIKLI Z. A., YURTTAŞ L., AKALIN ÇİFTÇİ G.
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.42, no.2, pp.131-137, 2017 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
42
Issue:
2
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Publication Date:
2017
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Doi Number:
10.1515/tjb-2016-0240
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Journal Name:
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.131-137
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Keywords:
1,3,4-Oxadiazole, Pyrimidine, Cytotoxic activity, ANTIINFLAMMATORY ACTIVITY, ANTICANCER AGENTS, ACID, OXADIAZOLE, INHIBITION, ANALOGS, SERIES
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Anadolu University Affiliated:
Yes
Abstract
Objective: As a result of adverse effects including drug-resistance, toxicity and low bioavailability, there has been a crucial need for novel anticancer agents. In this present study, some novel 2,5-disubstituted 1,3,4-oxadiazole derivatives bearing pyridine moiety were synthesized and their potential cytotoxic activities were examined.