Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells

Kuete, Victor; Omosa, Leonidah; Tala, Viviane; Midiwo, Jacob; Mbaveng, Armelle; Swaleh, Sauda; KARAOSMANOĞLU, OĞUZHAN; SİVAS, HÜLYA

doi:10.1186/s40360-016-0104-7

Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells

Kuete V., Omosa L. K., Tala V. R. S., Midiwo J. O., Mbaveng A. T., Swaleh S., ...More

BMC PHARMACOLOGY & TOXICOLOGY, vol.17, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 17
Publication Date: 2016
Doi Number: 10.1186/s40360-016-0104-7
Journal Name: BMC PHARMACOLOGY & TOXICOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Keywords: Carcinoma, cytotoxicity, Mode of action, Plumbagin, Quinones, Rapanone, CAMEROONIAN MEDICINAL-PLANTS, BREAST-CANCER, HERBAL MEDICINE, PHARMACOGENOMICS, INHIBITION, APOPTOSIS
Anadolu University Affiliated: Yes

Abstract

Background: Cancer is a major public health concern globally and chemotherapy remains the principal mode of the treatment of various malignant diseases.