Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells

Kuete, Victor; Omosa, Leonidah; Tala, Viviane; Midiwo, Jacob; Mbaveng, Armelle; Swaleh, Sauda; KARAOSMANOĞLU, OĞUZHAN; SİVAS, HÜLYA

doi:10.1186/s40360-016-0104-7

Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells

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Kuete V., Omosa L. K., Tala V. R. S., Midiwo J. O., Mbaveng A. T., Swaleh S., ...More

BMC PHARMACOLOGY & TOXICOLOGY, vol.17, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 17
Publication Date: 2016
Doi Number: 10.1186/s40360-016-0104-7
Journal Name: BMC PHARMACOLOGY & TOXICOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Keywords: Carcinoma, cytotoxicity, Mode of action, Plumbagin, Quinones, Rapanone, CAMEROONIAN MEDICINAL-PLANTS, BREAST-CANCER, HERBAL MEDICINE, PHARMACOGENOMICS, INHIBITION, APOPTOSIS
Anadolu University Affiliated: Yes

Abstract

Background: Cancer is a major public health concern globally and chemotherapy remains the principal mode of the treatment of various malignant diseases.