Cruise NOx emissions of aircraft are an important input parameter for studies investigating climate change due to their ability to alter the concentrations of certain trace gases, such as ozone, methane, and hydroxyl in the atmosphere, and to induce positive radiative forcing. Therefore, it is of importance to minimize estimation errors on NOx emitted from aircraft engines at high altitude. In this study, the cruise NOx emissions of a frequently-used narrow-bodied aircraft type operating domestic flights in Turkey, are quantified based on numerous actual flight, actual emissions and actual meteorological data. The overall average cruise NOx emissions index is found to be similar to 10 g/kg fuel. In addition, newly-developed parameters of the aircraft cruise NO. footprint and NOx intensity are calculated to be 0.5 g/pa-NM and similar to 60 g/NM, respectively. Regarding the effects of flight parameters on cruise NOx emissions, while there is a distinct increase in NOx parameters with an increase in aircraft mass, this may differ for altitude. The results reveal that the NOx emissions index tends to increase slightly by 1-2%, particularly above 28,000 ft, whereas NOx intensity decreases at a rate of 2.4-2.7% per 2000 ft of cruise altitude increase.