Cytotoxic, Antiproliferative and Apoptotic Effects of Perillyl Alcohol and Its Biotransformation Metabolite on A549 and HepG2 Cancer Cell Lines

Oturanel C. E., KIRAN İ., ÖZŞEN BATUR Ö., AKALIN ÇİFTÇİ G., ATLI EKLİOĞLU Ö.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.17, no.9, pp.1243-1250, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 9
  • Publication Date: 2017
  • Doi Number: 10.2174/1871520617666170103093923
  • Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1243-1250
  • Keywords: Anticancer, antiproliferative, apoptosis, biotransformation, cytotoxicity, perillyl alcohol, BIOLOGICAL EVALUATION, DERIVATIVES, ANTICANCER, MONOTERPENES, PREVENTION, EXPRESSION, DRUGS, ACID
  • Anadolu University Affiliated: Yes

Abstract

Background: A monoterpene, perillyl alcohol, has attracted attention in medicinal chemistry since it exhibited chemo-preventive and therapeutic properties against a variety of cancers.