Cytotoxic, Antiproliferative and Apoptotic Effects of Perillyl Alcohol and Its Biotransformation Metabolite on A549 and HepG2 Cancer Cell Lines

Oturanel, Ceren; KIRAN, İSMAİL; ÖZŞEN BATUR, ÖZGE; AKALIN ÇİFTÇİ, GÜLŞEN; ATLI EKLİOĞLU, ÖZLEM

doi:10.2174/1871520617666170103093923

Cytotoxic, Antiproliferative and Apoptotic Effects of Perillyl Alcohol and Its Biotransformation Metabolite on A549 and HepG2 Cancer Cell Lines

Atıf İçin Kopyala

Oturanel C. E., KIRAN İ., ÖZŞEN BATUR Ö., AKALIN ÇİFTÇİ G., ATLI EKLİOĞLU Ö.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.17, sa.9, ss.1243-1250, 2017 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 17 Sayı: 9
Basım Tarihi: 2017
Doi Numarası: 10.2174/1871520617666170103093923
Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1243-1250
Anahtar Kelimeler: Anticancer, antiproliferative, apoptosis, biotransformation, cytotoxicity, perillyl alcohol, BIOLOGICAL EVALUATION, DERIVATIVES, ANTICANCER, MONOTERPENES, PREVENTION, EXPRESSION, DRUGS, ACID
Anadolu Üniversitesi Adresli: Evet

Özet

Background: A monoterpene, perillyl alcohol, has attracted attention in medicinal chemistry since it exhibited chemo-preventive and therapeutic properties against a variety of cancers.