Copy For Citation
YURTTAŞ L., Evren A. E., Kubilay A., TEMEL H. E., AKALIN ÇİFTÇİ G.
LETTERS IN DRUG DESIGN & DISCOVERY, vol.17, no.12, pp.1502-1515, 2020 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
17
Issue:
12
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Publication Date:
2020
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Doi Number:
10.2174/1570180817999200712190831
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Journal Name:
LETTERS IN DRUG DESIGN & DISCOVERY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE
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Page Numbers:
pp.1502-1515
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Keywords:
Triazole, thiazole, apoptosis, MMP-9, caspase-3, A549, molecular modelling, BIOLOGICAL EVALUATION, ANTICANCER EVALUATION, CANCER-CELLS, APOPTOSIS, INHIBITORS, THIAZOLE, INDUCERS, DOCKING, HYBRIDS, DESIGN
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Anadolu University Affiliated:
Yes
Abstract
Background: Cancer is the name given to various diseases that are mainly uncontrolled, related to cell growth and can affect various organs. Among them, lung cancer is the one, which, in its earliest stages, is difficult to diagnose, and it is asymptomatic until the disease progresses. Triazole ring is an important heterocyclic ring known with various pharmacological activities.