Preparation of Activated Disposable Pencil Graphite Electrode for the Selective and Sensitive Determination of a Fluoroquinolone Antibiotic: Levofloxacin

Gurbuz M., Ozcan A. A., ÖZCAN A.

CURRENT PHARMACEUTICAL ANALYSIS, vol.14, no.3, pp.247-254, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.2174/1573412913666170317130625
  • Journal Name: CURRENT PHARMACEUTICAL ANALYSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.247-254
  • Keywords: Levofloxacin, pencil graphite, voltammetry, electrochemical overoxidation, electrode, fluoroquinolone, PERFORMANCE LIQUID-CHROMATOGRAPHY, GLASSY-CARBON ELECTRODE, FILM-MODIFIED ELECTRODE, VOLTAMMETRIC DETERMINATION, GOLD NANOPARTICLES, BIOLOGICAL-FLUIDS, WATER SAMPLES, BLOOD-SERUM, NANOTUBES, URINE
  • Anadolu University Affiliated: Yes

Abstract

Background: Levofloxacin (LVX) is one of the fluoroquinolone antibiotics that possess a wide spectrum of bactericidal activity against both Gram-positive and Gram-negative bacteria. Because of its side effects and its potential towards the development of antibiotic resistance, determination of this antibiotic is very important. New methods which have superior properties than the conventional methods are needed in the determination of pharmaceuticals in different samples.