A new protocol for the synthesis of primary, secondary and tertiary anthranilamides utilizing N-(2-aminoarylacyl)benzotriazoles

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KANIŞKAN N., Kokten S., ÇELİK İ.

ARKIVOC, vol.2012, pp.198-213, 2012 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 2012
  • Publication Date: 2012
  • Doi Number: 10.3998/ark.5550190.0013.818
  • Journal Name: ARKIVOC
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.198-213
  • Keywords: Anthranilic acid, benzotriazole, N-(2-aminoarylacyl)benzotrazoles, anthranilamides, BIOLOGICAL EVALUATION, N-ACYLBENZOTRIAZOLES, DERIVATIVES, INHIBITORS, RECEPTOR, IDENTIFICATION, BENZAMIDINES, CONVENIENT, EFFICIENT, ESTERS
  • Open Archive Collection: AVESIS Open Access Collection
  • Anadolu University Affiliated: Yes

Abstract

A convenient route for efficient conversion of unprotected anthranilic acids into the corresponding N-(2-aminoarylacyl)benzotrazoles is described. N-(2-Aminoarylacyl)benzotrazoles have been successfully used to synthesize primary, secondary and tertiary anthranilamides in high yields (71-96%).