EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol.36, no.7-8, pp.685-689, 2001 (SCI-Expanded)
The synthesis of some triazolyl-antipyrine derivatives starting from 4-chloroacetamidoantipyrine and 3-(aryloxyalkyl)-4-ethyl/phenyl-5-mercapto-1,2,4-triazoles is described. The chemical structures of the compounds were elucidated by IR, H-1-NMR and mass spectral studies. These compounds were tested for analgesic activity. (C) 2001 Editions scientifiques et medicales Elsevier SAS.