Synthesis of some triazolyl-antipyrine derivatives and investigation of analgesic activity
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, cilt.36, sa.7-8, ss.685-689, 2001 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 7-8
- Basım Tarihi: 2001
- Doi Numarası: 10.1016/s0223-5234(01)01252-1
- Dergi Adı: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
- Sayfa Sayıları: ss.685-689
- Anahtar Kelimeler: antipyrine, triazoles, analgesic activity
- Anadolu Üniversitesi Adresli: Hayır
Özet
The synthesis of some triazolyl-antipyrine derivatives starting from 4-chloroacetamidoantipyrine and 3-(aryloxyalkyl)-4-ethyl/phenyl-5-mercapto-1,2,4-triazoles is described. The chemical structures of the compounds were elucidated by IR, H-1-NMR and mass spectral studies. These compounds were tested for analgesic activity. (C) 2001 Editions scientifiques et medicales Elsevier SAS.