The purpose of the study is to systematically review studies investigating the script fading procedure on individuals with autism and also determine the quality of the studies and the effect size related to the calculations of the percentage of nonoverlapping data (PND) and the percentage of data exceeding the median (PEM) in the studies. The systematic review identified 32 articles reporting on the script fading procedure in individuals with autism aged between 3 and 19 years. Furthermore, a meta-analysis was conducted for 15 studies meeting the acceptability criteria within the scope of the Qualitative Indicators of Single-Subject Research indicated by Horner et al. (2005). The results of PND and PEM calculations showed that the SFP was highly effective in eight studies but moderately effective in four studies. The findings were discussed along with recommendations for future research.