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SEVER B., ALTINTOP M. D., AKALIN ÇİFTÇİ G., ÖZDEMİR A.
MEDICINAL CHEMISTRY, vol.17, no.10, pp.1104-1128, 2021 (SCI-Expanded)
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Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
Triazolothiadiazine, indole, colorectal cancer, non-small cell lung cancer, apoptosis, cell cycle arrest, COX-2, CYCLOOXYGENASE-2, INHIBITION, AKT
Anadolu University Affiliated:
Background: Targeted therapies acting on specific molecular targets in cancer cells with better curative efficacy and lower toxicity have come into prominence for the management of non-small cell lung cancer (NSCLC) and colorectal cancer (CRC). COX-2 stands out as a plausible target for anticancer agents due to its pivotal role in tumor initiation, progression and invasion.