Albumin Based Nanoparticles for Detection of Pancreatic Cancer Cells

Karaca N., Unluner O. B.

PROTEIN AND PEPTIDE LETTERS, vol.26, no.4, pp.271-280, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.2174/0929866526666190119121434
  • Journal Name: PROTEIN AND PEPTIDE LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.271-280
  • Keywords: Albumin nanoparticles, hyaluronic acid, ANADOLUCA method, pancreatic cancer, cell imaging, HA receptors, DRUG-DELIVERY, CD44
  • Anadolu University Affiliated: Yes

Abstract

Background: Molecular imaging of cancer cells using effective drug targeting systems are most interested research area in recent years. Albumin protein is a soluble and most abundant protein in circulatory system. It has a ligand-binding function and acts as a transport protein. Researchers are interested in developing albumin based nanostructured specific anti-tumor drugs in cancer therapy. Pancreatic cancer treatment or drug design for targeted pancreatic cancer cell has great importance due to it has a high mortality rate comparing other cancer types.