Psychopharmacological profile of Chamomile (Matricaria recutita L.) essential oil in mice

CAN Ö. D., DEMİR ÖZKAY Ü., KIYAN H. T., DEMİRCİ B.

PHYTOMEDICINE, vol.19, no.3-4, pp.306-310, 2012 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 19 Issue: 3-4
  • Publication Date: 2012
  • Doi Number: 10.1016/j.phymed.2011.10.001
  • Journal Name: PHYTOMEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.306-310
  • Keywords: Chamomilla recutita, Bisabolol, Caffeine, Psychostimulant, Anxiogenic, Tail-suspension, CENTRAL-NERVOUS-SYSTEM, TAIL SUSPENSION TEST, ANXIETY, RATS, CAFFEINE, FLOWERS, SEED
  • Anadolu University Affiliated: Yes

Abstract

In this study, the effect of Matricaria recutita L essential oil (MEO) on the central nervous system (CNS) of mice was investigated using some behavioral methods. Chemical profiling both by GC and GC-MS analyses of the hydrodistilled essential oil of M. recutita revealed alpha-bisabolol oxide A (28%), alpha-bisabolol oxide B (17.1%), (Z)-beta-Farnesene (15.9%) and alpha-bisabolol (6.8%) as the main components.