Synthesis of some 4-pyrrolylphenylthiazole derivatives and investigation of their antimicrobial activities

Demirayayak S., BENKLİ K., Sezer C., Erdeniz H.

Acta Pharmaceutica Turcica, vol.39, no.3, pp.133-136, 1997 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 3
  • Publication Date: 1997
  • Journal Name: Acta Pharmaceutica Turcica
  • Journal Indexes: Scopus
  • Page Numbers: pp.133-136
  • Keywords: Antibacterial, Antifungal effects, Pyrrole, Thiazole
  • Anadolu University Affiliated: Yes

Abstract

In this study, some 2-substituted 4-[4-(pyrrol-1-yl)phenyl] thiazole derivatives were obtained reacting some 1,4-dicarbonyl compounds and 2-substituted 4-(4-aminophenyl) thiazoles. The latters were prepared by hydrolyzing of 2-substituted 4-(4-acetylaminophenyl)thiazoles. The antibacterial and antifungal activities of the pyrrole compounds were investigated and no considerable activity was obtained.