This study determines and analyzes the principles of interactive scenario design supporting critical and creative thinking in asynchronous learning environments. The study was conducted as a qualitative research, framed by two theoretical approaches, heutagogy and inquiry-based learning, and a holistic case study. The basic principles of the theoretical approaches and then theoretical matrix where sixteen semi-structured interview questions transformed later on were the beginning of the study. Semi-structured interview questions were given to 7 open and distance learning field experts and the data was collected. For the data analysis descriptive and content analysis, for content analysis inductive analysis was used. NVivo12 was employed. The result of the study shows that in the design of interactive scenarios which is the basis of interactive videos, 4 main themes, which are (1) Support Productivity with Natural Curiosity, (2) Create Self-awareness, (3) Provide Self-discovery, (4) Spark off Intellectual Transformation, 16 themes describing the main themes and 55 sub-themes were achieved. The components leading the interactive scenario design where the themes explaining the main themes and the sub-themes take place were used as a checklist in the form of hypothesis.