Acrylamide-derived cytotoxic, anti-proliferative, and apoptotic effects on A549 cells

Kacar S., Vejselova D., Kutlu H. M., ŞAHİNTÜRK V.

HUMAN & EXPERIMENTAL TOXICOLOGY, vol.37, no.5, pp.468-474, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1177/0960327117712386
  • Journal Name: HUMAN & EXPERIMENTAL TOXICOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.468-474
  • Keywords: Acrylamide, A549, cytotoxicity, apoptosis, confocal microscopy, TEM, HUMAN ASTROCYTOMA-CELLS, INDUCED NEUROTOXICITY, HUMAN NEUROBLASTOMA, PROLIFERATION, DAMAGE
  • Anadolu University Affiliated: Yes

Abstract

Background: Acrylamide is a very common compound even reaching up to our daily foods. It has been studied in a wealth of cell lines on which it proved to have various toxic effects. Among these cell lines, human lung adenocarcinoma cell line (A549) is one of that on which acrylamide's toxicity has not been studied well yet.