Novel Tri-substituted Thiazoles Bearing Piperazine Ring: Synthesis and Evaluation of their Anticancer Activity

Evren A. E., YURTTAŞ L., Ekselli B., AKALIN ÇİFTÇİ G.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.16, no.5, pp.547-555, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.2174/1570180815666180731122118
  • Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.547-555
  • Keywords: Thiazole, azole, piperazine, acetamide, anticancer activity, phenyl, benzyl, BIOLOGICAL EVALUATION, ANTITUMOR-ACTIVITY, DERIVATIVES, INHIBITORS, DISCOVERY, POTENT, ANTIBACTERIAL, PATHWAYS, SURVIVAL, ANALOGS
  • Anadolu University Affiliated: Yes

Abstract

Background: Cancer cells are described as an unregulated growth and spread of abnormal cells. Recently, cancer has become the most important major reason for deaths in the world.