© 2015 Turkish National Committee for Air Pollution Research and Control. Production and hosting by Elsevier B.V. All rights reserved.Measurements for indoor air quality assessment were carried out in Painting and Printmaking Department of Anadolu University Faculty of Fine Arts in Turkey. Concentrations of nitrogen dioxide (NO2), ozone (O3) and 29 Volatile Organic Compounds (VOCs) were measured simultaneously by using diffusive samplers. Simultaneous outdoor measurements were also performed at some sampling points. Analyses of NO2 and ozone samples were performed by using ion chromatography and VOCs were analyzed by using gas chromatography-mass spectrometry. Indoor NO2 and ozone concentrations varied between 13.47–89.77 μg m–3 and 3.89–51.82 μg m–3, respectively. Average indoor NO2 concentration was obtained as 35.37 ± 10.9 mgm–3. Indoor/outdoor NO2 ratio (I/O) was found as 1.44 ± 0.4 which indicated the presence of some indoor sources. Average indoor ozone concentration was 9.97 ± 4.4 μg m–3 and I/O ratio was obtained lower than 1 (0.46 ± 0.4). The highest VOC concentrations were observed at workshops where oil painting and stained glass studies were performed. Especially, the concentrations obtained from the stained glass workshop (benzene: 3.98 ± 1.3 μg m–3, toluene: 999.33 ± 104.2 μg m–3, ethly benzene: 66.06 ± 16.1 mg m–3, m,p xylene: 129.44 ± 33.1 mg m–3, o-xylene: 76.14 ± 23.1 μg m–3) were much higher than the other sampling points. Toluene concentrations exceeded the WHO (World Health Organization) limit value (260 mg m–3 weekly average) at 40% of the sampling points. Cancer risks were estimated by using the personal exposure concentrations. Lifetime cancer risks for the people working in the department such as faculty members and technicians were obtained higher than USEPA acceptable risk value (1 × 10–6) while the risks for the students were below this value.