Effects of extracts from certain Sideritis species on swimming performance in mice

Ozturk Y., Aydin S., Ozturk N., Baser K.

PHYTOTHERAPY RESEARCH, vol.10, no.1, pp.70-73, 1996 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 1
  • Publication Date: 1996
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.70-73
  • Keywords: Sideritis species, swimming test, central nervous system, sedation, antistress activity, mice, BEHAVIORAL DESPAIR, MODEL, RATS
  • Anadolu University Affiliated: Yes


Extracts obtained from S. libanotica ssp. kurdica, S. lanata, S. perfoliata and S. athoa on mouse swimming performance were investigated using two different doses. In order to compare their effects on the swimming experiments, antidepressant drugs, desipramine and trimipramine, were also tested. On the basis of our findings, low doses (250 mg/kg) of these extracts from the Sideritis species decreased the swimming time, suggesting a central nervous system depressant activity, whereas central nervous system stimulant and/or antistress activities became evident at higher doses (500 mg/kg) of aqueous Sideritis extracts.