Moxifloxacin Hydrochloride-Loaded Eudragit (R) RL 100 and Kollidon (R) SR Based Nanoparticles: Formulation, In vitro Characterization and Cytotoxicity

YURTDAŞ KIRIMLIOĞLU G., ÖZER S., BÜYÜKKÖROĞLU G., Yazan Y.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, vol.24, no.3, pp.328-341, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.2174/1386207323666200428091945
  • Journal Name: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.328-341
  • Keywords: Moxifloxacin hydrochloride, nanoparticle, Eudragit (R) RL 100, Kollidon (R) SR, modified release, ocular delivery
  • Anadolu University Affiliated: Yes

Abstract

Background: Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need to design efficient novel drug delivery systems that may enhance precorneal retention time and corneal permeability.