Moxifloxacin Hydrochloride-Loaded Eudragit (R) RL 100 and Kollidon (R) SR Based Nanoparticles: Formulation, In vitro Characterization and Cytotoxicity

YURTDAŞ KIRIMLIOĞLU G., ÖZER S., BÜYÜKKÖROĞLU G., Yazan Y.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, cilt.24, sa.3, ss.328-341, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1386207323666200428091945
  • Dergi Adı: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.328-341
  • Anahtar Kelimeler: Moxifloxacin hydrochloride, nanoparticle, Eudragit (R) RL 100, Kollidon (R) SR, modified release, ocular delivery
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need to design efficient novel drug delivery systems that may enhance precorneal retention time and corneal permeability.