Formulation and in-vivo evaluation of a cosmetic multiple emulsion containing vitamin C and wheat protein
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.21, sa.1, ss.45-50, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 1
- Basım Tarihi: 2008
- Dergi Adı: PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.45-50
- Anahtar Kelimeler: multiple emulsion, vitamin C, wheat proteins, dermatological evaluation, ASCORBIC-ACID, COLLAGEN-SYNTHESIS, SKIN FIBROBLASTS, ERYTHEMA, RELEASE
- Anadolu Üniversitesi Adresli: Evet
Özet
The purpose of the study was to see the effect of two antiaging agents in one stable multiple emulsion prepared using natural oil. Vitamin C, which is a very unstable ingredient and is decomposed in the presence of oxygen, active as an antioxidant, was entrapped in the inner aqueous phase of w/o/w multiple emulsion. In this way, slow release can be expected and the effect of vitamin C can be increased since it is protected from the external environment by entrapping it in the internal phase. The other ingredient which is a product of wheat proteins was also used as an antiaging agent in the oily phase. Both of the ingredients increase the synthesis of collagen fibers in the dermis. Therefore, a synergystic effect can be produced by using the two ingredients in one formulation.