Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes

Gündoğdu-Karaburun N., Benkli K., Tunali Y., Ucucu U., Demirayak S.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, cilt.41, sa.5, ss.651-656, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.ejmech.2005.12.013
  • Dergi Adı: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
  • Sayfa Sayıları: ss.651-656
  • Anahtar Kelimeler: aryl [3-(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketoximes, antifungal activity, OXIME ETHER DERIVATIVES, FUNGICIDAL ACTIVITY, CANDIDA-ALBICANS, AGENTS, SORDARICIN, ANALOGS
  • Anadolu Üniversitesi Adresli: Evet

Özet

In this study, some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketones, aryl (3-methyl-benzofuran-2-yl) ketoximes and aryl [3(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketoximes were synthesised starting from 2-aryloyl-3-methyl-benzofuranes. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. Antifungal activities of the compounds were examined and moderate activity was obtained. (c) 2006 Elsevier SAS. All rights reserved.