LETTERS IN DRUG DESIGN & DISCOVERY, vol.14, no.5, pp.554-566, 2017 (SCI-Expanded)
Background: Cancer is one of the leading causes of morbidity and mortality worldwide and extensive efforts have been devoted to the discovery of new anticancer agents. In the last few decades, the clinical efficacy of tiazofurin and its analogues, dasatinib and bleomycins has pointed out the importance of thiazole moiety in the field of cancer treatment.