Synthesis of New Bis-pyrazolines Endowed with Potent Antifungal Activity against Candida albicans and Aspergillus niger

SEVER B., ALTINTOP M. D., ÖZDEMİR A.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.18, sa.1, ss.3-15, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1570180817999201008155247
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
  • Sayfa Sayıları: ss.3-15
  • Anahtar Kelimeler: Bis-pyrazoline, dithiocarbamate, oxadiazole, antifungal activity, aspergillosis and candidiasis, BIOLOGICAL EVALUATION, DERIVATIVES BEARING, DRUG-RESISTANCE, GROWTH, DISCOVERY, VIRULENCE, MOIETY
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: Due to the increasing number of cases of invasive fungal infections (IFIs), there is an urgent need to identify potent antifungal agents capable of combating IFIs. Pyrazolines are one such class of therapeutically active agents that could be considered to fulfill this need.