BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol.16, 2016 (SCI-Expanded)
Article / Article
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Cell cycle, Cisplatin, JNK, MAPK, Mesothelioma, Quercetin, p38, APOPTOSIS, P38, INHIBITION, PATHWAYS, JNK, ERK, P53, PHOSPHORYLATION, PREVENTION, COMPLEX
Anadolu University Affiliated:
Background: Malignant mesothelioma is a locally aggressive and highly lethal neoplasm of pleural, peritoneal and pericardial mesothelial cells without successful therapy. Previously, we reported that Quercetin in combination with Cisplatin inhibits cell proliferation and activates caspase-9 and -3 enzymes in different malignant mesothelioma cell lines. Moreover, Quercetin + Cisplatin lead to accumulation of both SPC111 and SPC212 cell lines in S phase.