Synthesis and Anticancer Activity of New Hydrazide-hydrazoncs and Their Pd(II) Complexes

KAYMAKÇIOĞLU B., Yazici S. S., TOK F., DİKMEN M., Engur S., Oruc-Emre E. E., ...More

LETTERS IN DRUG DESIGN & DISCOVERY, vol.16, no.5, pp.522-532, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.2174/1570180815666180816124102
  • Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.522-532
  • Keywords: Hydrazone, metal-complexes, anticancer activity, MTT assay, real-time monitoring, proliferative system, IN-VITRO, PROTEIN-BINDING, PLATINUM(II) COMPLEXES, CRYSTAL-STRUCTURE, DNA-BINDING, PALLADIUM(II), DERIVATIVES, LIGANDS, PROLIFERATION, ANTIOXIDANT
  • Anadolu University Affiliated: Yes

Abstract

Background: Hydrazones, one of the important classes of organic molecules, are pharmaceutical agents comprising -CO-NH-N=CH- group in the structure therefore and exhibiting significant biological activity.