Synthesis and Characterization of Two New Thiophene Acetyl Salicylic Acid Esters and their ortho-and para-effect on Anticancer Activity

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ÜNVER H., CANTÜRK Z.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.17, no.10, pp.1383-1388, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 17 Issue: 10
• Publication Date: 2017
• Doi Number: 10.2174/1871520617666170213113843
• Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1383-1388
• Keywords: A549, Caco2, cancer, MTT, thiophene acetic acid ester, anticancer activity, COLON-CANCER CELLS, NITRIC-OXIDE, BIOLOGICAL-ACTIVITY, DERIVATIVES, ASPIRIN, PHENOTHIAZINE, INHIBITORS, PESTICIDE, DESIGN, GROWTH
• Anadolu University Affiliated: Yes

Abstract

Objective: The present study aimed to explore the cytotoxic effect of ortho-and para-positional isomers of thiophene acetyl salicylic acid esters against cancer and normal cell lines.