Niclosamide Suppresses Proliferation, Induces Apoptosis and Inhibits Wnt/beta-catenin Signaling Pathway in Human Ovarian Cancer Cells

Creative Commons License

Gundogdu A. C., TAKE KAPLANOĞLU G., SİVAS H., Varol R., SEYMEN C. M.

GAZI MEDICAL JOURNAL, cilt.30, sa.2, ss.178-183, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.12996/gmj.2019.43
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.178-183
  • Anahtar Kelimeler: OVCAR-3, niclosamide, 5-fluorouracil, Wnt/beta-catenin, proliferation, apoptosis, MECHANISMS, ERLOTINIB, PROTEINS, ANALOGS, GROWTH, STAT3
  • Anadolu Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study is to investigate in vitro effects of an antihelminthic drug niclosamide on human ovarian carcinoma cell line OVCAR3.