Study on the Antimicrobial Effects of Novel Thiazole Derivatives

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YILMAZ CANKILIÇ M., YURTTAŞ L.

MARMARA PHARMACEUTICAL JOURNAL, cilt.21, sa.3, ss.654-659, 2017 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.12991/marupj.323584
  • Dergi Adı: MARMARA PHARMACEUTICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.654-659
  • Anahtar Kelimeler: antibacterial, antifungungal, thiazole, LOCAL-ANESTHETIC ACTIVITY, GROWTH, ASSAYS
  • Anadolu Üniversitesi Adresli: Evet

Özet

In this work, six 2-[(1/4-methylimidazol/triazol/tetrazol-2/3/5-yl) thio]-N-(4-substituted thiazol-2-yl) acetamide derivatives (2a-f) were synthesized. The antimicrobial activities of these substances were examined against some foodborne Gram positive and Gram negative test bacteria, Candida albicans, Candida glabrata, Candida krusei, and Candida parapsilosis yeasts, and some Aspergillus and Penicillium filamentous fungi species. The substances were shown considerable antimicrobial effect to tested pathogenic microorganisms.