In this study, the new constraints which can lie applied in network design problem are developed by taking especially the sectoral features of air transportation and aircraft types into consideration. A new mixed integer linear programming model is developed by including the new constraints into the traditional model of uncapacitated single allocation median problem accordingly. The aim of this study is to analyze the effects of the new constraints on the hub location. The model is tested by using Turkish air cargo statistics and the data related to the aircraft types, A300-B4 and F27500. The results of the analysis show that the new constraints and the aircraft types used in air cargo transportation have the significant effects on the hub locution problem.