Composition and antimicrobial activity of the oils of Ferula szowitsiana DC. from Turkey

Oezek G., ÖZEK T., İŞCAN G., BAŞER K. H. C., DURAN A., Hammoglu E.

JOURNAL OF ESSENTIAL OIL RESEARCH, vol.20, no.2, pp.186-190, 2008 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2008
  • Doi Number: 10.1080/10412905.2008.9699987
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.186-190
  • Keywords: Ferula szowitsiana, Umbelliferae, essential oil composition, beta-eudesmol, alpha-eudesmol, antimicrobial activity, SINAICA ROOT EXTRACT, PIG SMOOTH-MUSCLE, GUINEA-PIG, ANTIBACTERIAL ACTIVITY, SESQUITERPENES, IDENTIFICATION, CONSTITUENTS, FRUITS, RABBIT
  • Anadolu University Affiliated: Yes


The essential oils from the leaves and steins of Ferula szowitsiana DC. (Umbelliferae) were separately obtained by hydrodistillation and then analyzed by GC and GC/MS methods. The oil yields were 0.4% and 0.05%, respectively. One-hundred and sixty-two compounds representing 99.5% and 99 compounds representing 94.4% were identified in the leaf oil and stem oil, respectively, with beta-eudesmol (32.0% and 29.5%, resp.), alpha-eudesmol (18.2% and 16.6%, resp.) and alpha-pinene (8.6% and 6.4%, resp.) as the major constituents. Antimicrobial activity of the leaf oil was tested via in-vitro microdilution broth technique. Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, Salmonella typhimurium, Staphylococcus epidermidis, Methicillin-resistant Staphylococcus aureus, and Candida albicans were used as the test microorganisms.