Watershed models that combine hydrology and water quality are being widely used in integrated watershed management for the determination of best water management practices. In this study, the hydrology of the Lower Porsuk Stream Watershed in Turkey has been modelled with the Soil and Water Assessment Tool to determine optimal water management strategies. The calibration and the validation process have been accomplished using data from two monitoring stations. The model has been run for the 1978-2009 period, and while the 1998-2004 period has been used for calibration, the validation has spanned the whole period. The SWATCup calibration and uncertainty program has been used for this purpose. No significant differences have been detected among different iteration numbers in the calibration period. The monthly Nash-Sutcliffe and R-2 performance indicators for the upstream Esenkara station have been 0.74 and 0.88, respectively, for the calibration period, and 0.87 and 0.87, respectively, for the validation period. The Kiranharmani station, which is located close to the watershed outlet, has shown values of 0.59 and 0.72, respectively, for the calibration period, and 0.44 and 0.56, respectively, for the validation period. There are uncertainties in the abstracted irrigation and groundwater quantities that have reflected in the results in the Kiranharmani station, which is more affected as it lies downstream of the irrigation areas. The effects of different irrigation practices on the flow regime have been also investigated. A scenario has been implemented in which drip irrigation wholly replaces conventional furrow and sprinkler irrigation. The scenario has shown increases in stream flows by 87% for the whole year. The adoption of more efficient irrigation practices thus results in reducing the water stress induced by irrigation demands. With this study, a modelling framework has been founded to aid water management applications in the Lower Porsuk Stream Watershed by generating scenarios for best management practices. Copyright (C) 2012 John Wiley & Sons, Ltd.